Studies on the environmental and genetic factors of the host that are determinant in the occurrence of infections and in the different clinical manifestations of the disease can contribute to the understanding of the dynamics of diseases and their maintenance at different levels of prevalence in populations. We analyze patient location data to understand the impact of spatial dispersion, an important factor in vector-borne diseases, arbovirus and malaria infections.

In the field of infectious diseases such as malaria and arboviruses, it is known that in addition to environmental factors, the genetic factors of the host also have a very important influence, especially in the fate of an infection and in the diversity of forms of manifestation of the disease. Therefore, we are working on the definition of phenotypes and the search for associated genes.

Genetic data are often very complex because of their abundance and the formats in which they can be presented (depending on the technology of origin). Depending on the scientific questions relating to our different themes, a variety of statistical methods can be useful. Thus, we are developing IT tools allowing the cleaning and standardization of data, often received in raw form, and their integration into automatic analysis pipelines using a certain number of existing tools.

The Study of Environmental Factors is one of the first steps in our search for determining factors in infectious diseases, particularly vector-borne. These factors play a major role in exposure and the onset of infections, but also in the development and progression of the disease by interacting with the host's genetic factors. We are working on statistical methods to identify and understand the role of these factors.